阿奇霉素

产品名称

中文名

阿奇霉素
英文名

Azithromycin
中文别名

阿齐霉素 | 阿奇霉素杂质 B

英文别名

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-on

Azithromycin

Ribotrex

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,

2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside

MFCD00873574

Tobil

Zistic

Azithral

Arzomicin

Zithromac

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl

xz405

Aztrin

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

Setron

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b η-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(diméthylamino)-3-hydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-2-éthyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-méthoxy-4,6-diméthyltétrahydro-2H-pyran-2-yl]oxy}-3,5,6,8,10,12,14-heptaméthyl-1-oxa-6-azacyclopentadécan-15-one

Aruzilina

Zeto

1-oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

Azadose

Aziwok

Azimin

Azenil

9-Deoxo-9a-methyl-9a-aza-9a-homoerythromycin A

azithromycinum [INN_la]

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside

XZ-450

Zifin

Ultreon

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

常用名

阿奇霉素
C A S号

83905-01-5

物理性质

密度

1.2±0.1 g/cm3
沸点

822.1±65.0 °C at 760 mmHg
熔点

113-115°C
化学式

C₃₈H₇₂N₂O₁₂
结构式
闪点

451.0±34.3 °C
分子量

748.984
精确质量

748.508545
P S A

180.08000
外观形状

白色结晶粉末
储存条件

Store at -20°C
稳定性
水溶解性
形态
H L B值
粘度
PH值

作用/用途

Azithromycin 是一种大环内酯抗生素，常用于治疗细菌感染。

制备方法

以红霉素A为原料，经肟化后，在盐酸作用下进行Beckmann重排，再脱水、还原、甲基化可得阿奇霉素.

83905-01-5 preparation

安全提醒

MSDS

原料简介

应用范围

毒性和生态

安全信息

符号	GHS08
信号词	Danger
危害声明	H317-H334
警示性声明	P261-P280-P342 + P311
个人防护装备	Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	42/43
安全声明 (欧洲)	22-36/37-45
危险品运输编码	NONH for all modes of transport
RTECS号	RN6960000
海关编码	2941500000

是否危险品

危险性

危险类别码

危险等级

触发危险方式

安全技术说明书

环境影响程度

包装与储运