N-(Azido-PEG4)-N-bis(PEG4-NHS ester) E3 ligase Ligand-Linker Conjugates 49 叠氮-二聚乙二醇 tert-Butyl 11-aminoundecanoate 溴代-四聚乙二醇 Tos-PEG5-C2-Boc Cbz-NH-PEG5-CH2COOH Fmoc-PEG1-CH2CH2-NHS ester Methyltetrazine-PEG8-NHS ester Fmoc-PEG6-NHS ester t-Boc-Aminooxy-PEG5-azide 6-氨基氧基己酸氢溴酸盐 对甲苯磺酸酯-四聚乙二醇-四氢吡喃醚 叠氮-十聚乙二醇-羧酸 Folate-PEG3-alkyne Bromo-PEG1-C2-azide N-(Biotin-PEG4)-N-bis(PEG4-Boc) Lipoamido-PEG12-acid Methylamino-PEG5-azide Boc-NH-PEG4-Ms 1,14-二溴-3,6,9,12-四恶十四烷 N-Biotin-N-bis(PEG4-acid) 3,4-Dibromo-Mal-PEG4-Boc Sulfone-Bis-PEG4-acid 5,8,11-三氧杂-2-氮杂十三烷二酸-1-叔丁酯 N-(Boc-PEG5)-N-bis(PEG4-acid) NH-bis(m-PEG8) m-PEG24-alcohol 13-氨基-5,8,11-三氧杂-2-氮杂十三烷酸 1,1-二甲基乙酯 Mal-amido-PEG2-TFP ester m-PEG3-S-PEG4-propargyl HO-PEG8-CH2COOH 2-(Azido-PEG2-amido)-1,3-propandiol 羧酸-五聚乙二醇-羧酸 PROTAC Linker 7 TCO-PEG3-amide-C3-triethoxysilane Pip-alkyne-Ph-COOCH3 BDP FL-PEG5-propargyl m-PEG4-CH2COOH N-(acid-PEG3)-N-bis(PEG3-azide) N-(Azido-PEG3)-NH-PEG3-acid TCO-PEG4-biotin E3连接酶配体1 六甘醇单甲醚丙酸叔丁酯 ERD-308 Methyltetrazine-PEG5-alkyne Butoxycarbonyl-PEG5-sulfonic acid Azido-PEG9-azide Azido-PEG7-azide Thiol-PEG6-acid PROTAC Linker 4 4-(N-马来酰亚胺基甲基)环己基甲酸 β-Estradiol-6-one 6-(O-carboxymethyloxime) Propargyl-peg3-sulfone-peg3-propargyl Thalidomide-5-OH Hexane-1,6-diyldiphosphonic acid Biotin-PEG6-Thalidomide 5,8,11,14,17-五氧杂-2-氮杂二十碳二酸 1-(9H-芴-9-基甲基)酯 Mal-amido-PEG12-acid PROTAC AR Degrader-4 Ald-Ph-amido-PEG2-C2-Boc TCO-PEG4-TCO m-PEG4-CH2-aldehyde E3 ligase Ligand-Linker Conjugates 39 HS-PEG11-CH2CH2N3 Pyrene-amido-PEG4-CH2CH2COOH Pomalidomide-PEG1-azide t-Boc-Aminooxy-PEG2-azide Methylamino-PEG4-Boc Thalidomide-O-PEG4-amine Mal-NH-PEG6-CH2CH2COOPFP ester Methyltetrazine-PEG24-amine N-Me-N-bis(PEG4-acid) (S,R,S)-AHPC-Me-C5-COOH TAMRA-PEG4-Alkyne E3 ligase Ligand-Linker Conjugates 33 VH032-PEG1-NH2 dihydrochloride Cbz-NH-PEG12-C2-acid E3 ligase Ligand 17 hydrochloride Aldehyde-benzyl-PEG5-alkyne (S,R,S)-AHPC-C8-NH2 Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane DNP-PEG3-azide Pyrene-PEG5-propargyl E3 Ligase Ligand-Linker Conjugates 1 Thalidomide-NH-PEG2-C2-NH2 hydrochloride Propargyl-PEG13-alcohol m-PEG17-acid Fluorescein-PEG6-bis-NHS ester 苄基-二聚乙二醇-叠氮 m-PEG5-phosphonic acid 1,1,1-Trifluoroethyl-PEG2-propargyl Azido-PEG4-tetra-Ac-beta-D-glucose 叠氮-六聚乙二醇-羧酸 t-Boc-aminooxy-PEG6-propargyl Methyltetrazine-amido-PEG5-alkyne 甲胺基-三聚乙二醇-羧酸 DBCO-NH-Boc (S,R,S)-AHPC-C6-NH2 dihydrochloride (S,R,S)-AHPC-C10-NH2 dihydrochloride (S,R,S)-AHPC-PEG2-NH2 dihydrochloride E3 ligase Ligand-Linker Conjugates 38 DBCO-PEG1-amine m-PEG6-Ms Cbz-NH-PEG3-C2-acid E3连接酶Ligand-Linker共轭物18 E3 Ligase Ligand-Linker Conmaugates 24 TFA A 410099.1, amine-Boc hydrochloride endo-BCN-PEG4-PFP ester SPDP-C6-NHS ester Propargyl-PEG2-N-bis(PEG2) PROTAC Linker 5 2-[2-(叔丁氧羰基氨基)乙氧基]乙氧基乙酸 Bromoacetamido-PEG3-azide BM-PEG3 E3连接酶Ligand-Linker共轭物7 Protac连接子5 对甲苯磺酸酯丙酸叔丁酯乙二醇 Tos-PEG4-CH2-Boc Cbz-NH-PEG1-CH2COOH (S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride Thalidomide-O-C6-NH2 TFA Thalidomide-O-amido-PEG-C2-NH2 hydrochloride PC-Biotin-PEG4-NHS carbonate C2-Bis-phosphoramidic acid diethyl ester N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 三聚乙二醇-羧酸 Acid-PEG4-mono-methyl ester Mal-PEG5-acid (S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride E3连接酶Ligand-Linker共轭物16 m-PEG3-NHS ester N-(m-PEG4)-N'-(amino-PEG3)-Cy5 Bromoacetamido-PEG4-C2-Boc Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 m-PEG4-sulfonic acid Thalidomide-O-amido-C4-NH2 hydrochloride Mal-amide-PEG2-oxyamine-Boc endo-BCN-PEG3-NH2 m-PEG2-Ms E3连接酶Ligand-Linker共轭物11 Fmoc-NMe-PEG4-NHS ester E3 Ligase Ligand-Linker Conjugates 2 (S,R,S)-AHPC-C5-NH2 hydrochloride N-Boc-N-bis(PEG2-propargyl) N-[2-[2-[3-[(2,5-二氧代-1-吡咯烷基)氧基]-3-氧代丙氧基]乙氧基]乙基]六氢-2-氧代-1H-噻吩并[3,4-D]咪唑-4-戊酰胺 Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride Fluorescein-thiourea-PEG6-acid TCO-PEG2-amine Mal-PEG4-Boc E3连接酶Ligand-Linker Conjugates 12 (S,R,S)-AHPC-C4-NH2 dihydrochloride (S,R,S)-AHPC-Me-C10-NH2 Thalidomide-NH-PEG2-C2-NH-Boc N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid Pomalidomide-amido-C3-COOH m-PEG8-Mal E3连接酶配体-连接体共轭25个三氟乙酸盐 SPDP-PEG6-NHS ester DNP-PEG4-DBCO E3 ligase Ligand-Linker Conjugates 40 Bis-PEG4-sulfonic acid DBCO-PEG2-acid (S,R,S)-AHPC-C2-NH2 dihydrochloride Pomalidomide 4'-alkylC5-acid E3 ligase Ligand-Linker Conjugates 21 苄基-乙二醇-氨基 Propargyl-PEG3-SH Pomalidomide-PEG4-C2-NH2 hydrochloride N-(PEG1-OH)-N-Boc-PEG2-propargyl 十二乙二醇单甲醚丙酸 4,7,10,13,16,19,22-七氧杂二十三烷酸 Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Thalidomide-O-C4-NH2 hydrochloride Tos-PEG6-OH Hydroxy-PEG2-CH2COOH N-(Azido-PEG4)-biocytin Propargyl-PEG3-methane Lipoamido-PEG2-OH PEG4-bis(phosphonic acid diethyl ester) 溴代-三聚乙二醇-羧酸 Pyrene-PEG2-azide Thalidomide-NH-C4-NH-Boc Pomalidomide-PEG6-butyl iodide N-叔丁氧羰基-七聚乙二醇-羧酸 对甲苯磺酸酯丙酸叔丁酯六乙二醇 N-DBCO-N-bis(PEG2-C2-NHS ester) 七甘醇单甲醚